News & Information

  • A Nanotechnology Delivery System for EndoFine®

    January 18, 2013
    A Nanotechnology Delivery System for EndoFine®

    Adjuvants Plus Inc. is pleased to announce the successful acquisition of a license from Cornell University to access a nanotechnology delivery system for biologicals under the patent application “Nanosystems for Formulations of Effective Minimum Risk Biocides.”

    Biologicals, rightly or wrongly, are being held to the same standards for efficacy and overall performance as conventional pesticides even though they offer other benefits. To deliver superior results, conventional pesticides are typically used in combination with surfactants, water conditioning agents and other “add ins”; those combinations have not been generally used with living biopesticides and inoculants such as EndoFine. We recognize that the performance of biologicals would be enhanced from combination uses with other technologies. The survival of living organisms in the presence of many of these chemistries has been a hurdle. The efficacy for both fungal and bacterial biopesticides and inoculants may be improved with the application of nanotechnology.

    This nanoencapsulation or incorporation system uses cyclodextrins as the base material. Cyclodextrins are composed of a circular structure of 6-8 glucose units with a hydrophobic inner core and hydrophilic outer layer. Within the central cyclodextrin core, hydrophobic materials are tightly bound, but weaker binding also may occur on the outer portion. Cyclodextrins are unaffected by
    shear forces and are readily dispersible in liquids.

    This technology provides a method to prevent surfactants and other chemicals from adversely affecting the viability of biocontrol agents and inoculants. Surfactants contain both polar and non polar regions, and can be sequestered by cyclodextrins. A surfactant would physically be located within the cyclodextrins and thereby would not come into contact with the biological agent while in storage. The surfactant would then be released when exposed to water. In addition, complex formulations used in integrated pest management programs may contain both conventional chemistries in combination with biologicals. Most pesticides are nonpolar and as such, can also be sequestered by cyclodextrins and removed from contact with biological agents while in storage.

    The scope contained within this nanotechnology licensing agreement includes composition and methods of use to produce formulations with excellent handling characteristics and water-activated release systems. Combinations within formulations can include additives, adjuvants and synergists to enhance the activity of various biologicals.

    Adjuvants Plus Inc. is committed to developing its biologicals product portfolio, as a tool within an integrated pest management program, to meet the needs of row crop and horticultural crop growers worldwide. Adjuvants Plus will continue to seek marketing partners for its biological product line to ensure that the technology can contribute toward meeting the increasing demand for global food production. We look forward to advancing our knowledge of the EndoFine technology platform using nanotechnology and other innovations.